Tmem79 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Involved in several processes, including epithelial cell maturation; establishment of skin barrier; and positive regulation of epidermis development. Acts upstream of or within cornification; cuticle development; and hair follicle morphogenesis. Located in lysosomal membrane and trans-Golgi network membrane. Is expressed in alimentary system; genitourinary system; naris; skin; and thymus. Used to study atopic dermatitis. Orthologous to human TMEM79 (transmembrane protein 79). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem79 |
| Official Name | transmembrane protein 79 [Source:MGI Symbol;Acc:MGI:1919163] |
| Ensembl ID | ENSMUSG00000001420 |
| Bio databases IDs | |
| Aliases | transmembrane protein 79 |
| Synonyms | 2310042N02Rik, 2310074C17Rik, ma, MATT, MGC13102, RGD1309886, transmembrane protein 79 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem79 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- trans Golgi network
- lysosome membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem79 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of epidermis development
- epithelial cell maturation
- regulated secretory pathway
- hair follicle morphogenesis
- cornification
- cuticle development
- establishment of skin barrier
Cellular Component
Where in the cell the gene product is active
- lysosomal membrane
- trans-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding