Apoc2

Predicted to enable several functions, including identical protein binding activity; lipase activator activity; and phospholipase binding activity. Predicted to be involved in several processes, including negative regulation of transport; positive regulation of lipase activity; and regulation of lipid metabolic process. Predicted to be located in extracellular space. Predicted to be part of several cellular components, including low-density lipoprotein particle; spherical high-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Is expressed in several structures, including capillary; central nervous system; liver; lung; and yolk sac endoderm. Human ortholog(s) of this gene implicated in familial apolipoprotein C-II deficiency; familial hyperlipidemia; and multiple sclerosis. Orthologous to human APOC2 (apolipoprotein C2). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Apoc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Apoc2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Apoc2 gene, providing context for its role in the cell.