Npdc1 Gene Summary [Mouse]
Predicted to be located in membrane. Is expressed in several structures, including axial skeleton; central nervous system; metanephros; neural retina; and thymus. Orthologous to human NPDC1 (neural proliferation, differentiation and control 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Npdc1 |
| Official Name | neural proliferation, differentiation and control 1 [Source:MGI Symbol;Acc:MGI:1099802] |
| Ensembl ID | ENSMUSG00000015094 |
| Bio databases IDs | |
| Aliases | neural proliferation, differentiation and control 1 |
| Synonyms | CAB-, CAB-1, neural proliferation, differentiation and control 1, neural proliferation, differentiation and control, 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Npdc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PEST domain
- membrane-association domain
- helix-loop-helix domain
- protein binding
- Neural proliferation differentiation control-1 protein (NPDC1)
- hydrophobic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- systemic lupus erythematosus
- Alzheimer disease
- Down syndrome
- pemphigus foliaceus
role in cell
- proliferation
- transformation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell surface
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Npdc1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding