Rps13 Gene Summary [Mouse]
A structural constituent of ribosome. Predicted to be involved in negative regulation of RNA splicing and ribosomal small subunit biogenesis. Part of cytosolic small ribosomal subunit. Orthologous to human RPS13 (ribosomal protein S13). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps13 |
| Official Name | ribosomal protein S13 [Source:MGI Symbol;Acc:MGI:1915302] |
| Ensembl ID | ENSMUSG00000090862 |
| Bio databases IDs | |
| Aliases | ribosomal protein S13 |
| Synonyms | 2700063M04Rik, ribosomal protein S13, S13, uS15 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal S13/S15 N-terminal domain
- structural constituent of ribosome
- mRNA 5' UTR binding
- rRNA binding
- Ribosomal protein S15
- mRNA binding
- S15_NS1_EPRS_RNA-bind
- protein binding
Pathways
Biological processes and signaling networks where the Rps13 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- rheumatoid arthritis
- flu
- nonalcoholic fatty liver disease
- lymphoma
- lymphomagenesis
regulates
- RNR
role in cell
- cell death
- processing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pre-ribosome
- ribosome
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
- synapse
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- ribosomal small subunit biogenesis
- negative regulation of RNA splicing
- translation
Cellular Component
Where in the cell the gene product is active
- postsynaptic density
- small-subunit processome
- cytosolic ribosome
- cytosolic small ribosomal subunit
- ribosome
- nucleolus
- nucleoplasm
- nucleus
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- mRNA 5'-UTR binding
- mRNA binding
- SSU rRNA binding