Ddx50 Gene Summary [Mouse]
Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be located in plasma membrane. Predicted to be active in nucleolus. Is expressed in embryo. Orthologous to human DDX50 (DExD-box helicase 50). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ddx50 |
| Official Name | DExD box helicase 50 [Source:MGI Symbol;Acc:MGI:2182303] |
| Ensembl ID | ENSMUSG00000020076 |
| Bio databases IDs | |
| Aliases | DExD box helicase 50 |
| Synonyms | 4933429B04Rik, 8430408E17RIK, DExD-box helicase 50, GU2, GUB, mcdrh, RH-II, RH-II/GuB, Similar to gu2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ddx50 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- helicase superfamily c-terminal domain
- DEAD/DEAH box helicase
- Type III restriction enzyme, res subunit
- N-terminal helicase domain of the DEAD-box helicase superfamily
- enzyme
- DEAD-like helicases superfamily
- CRISPR-associated helicase Cas3
- RNA-binding GUCT domain found in the RNA helicase II/Gu protein family
- Helicase conserved C-terminal domain
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Plasma Membrane
- nucleoli
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ddx50 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
- nucleolus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- RNA binding
- RNA helicase activity
- mRNA binding