Arpc2

Predicted to enable ATPase binding activity; actin filament binding activity; and glutamate receptor binding activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within positive regulation of actin filament polymerization and positive regulation of substrate adhesion-dependent cell spreading. Located in several cellular components, including endosome; focal adhesion; and muscle cell projection membrane. Is active in glutamatergic synapse; postsynapse; and synaptic vesicle membrane. Is expressed in lens and lens pit. Orthologous to human ARPC2 (actin related protein 2/3 complex subunit 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Arpc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Arpc2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Arpc2 gene, providing context for its role in the cell.