Cdca7l Gene Summary [Mouse]
Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within positive regulation of cell population proliferation. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; genitourinary system; gut; respiratory system; and sensory organ. Orthologous to human CDCA7L (cell division cycle associated 7 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Cdca7l |
| Official Name | cell division cycle associated 7 like [Source:MGI Symbol;Acc:MGI:2384982] |
| Ensembl ID | ENSMUSG00000021175 |
| Bio databases IDs | |
| Aliases | cell division cycle associated 7 like |
| Synonyms | cell division cycle associated 7 like, DKFZp762L0311, JPO2, R1, RAM2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cdca7l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc-finger domain of monoamine-oxidase A repressor R1
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- head and neck neoplasia
- lymphoma
- brain cancer
- head and neck cancer
- cancer
- lymphomagenesis
- primary ciliary dyskinesia 7
- primary ciliary dyskinesia
- metastasis
- latent tuberculosis
role in cell
- survival
- proliferation
- colony formation
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- fibrillar center
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cdca7l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of cell proliferation
- regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- nucleolus
- fibrillar center
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding