Prelid1 Gene Summary [Mouse]
Predicted to enable phosphatidic acid transfer activity. Involved in negative regulation of apoptotic process. Located in mitochondrion. Is expressed in several structures, including brain; gonad; immune system; liver; and stomach. Orthologous to human PRELID1 (PRELI domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prelid1 |
| Official Name | PRELI domain containing 1 [Source:MGI Symbol;Acc:MGI:1913744] |
| Ensembl ID | ENSMUSG00000021486 |
| Bio databases IDs | |
| Aliases | PRELI domain containing 1 |
| Synonyms | 2610524G07Rik, CGI-106, PRELI, PRELI domain containing 1, PX19, RGD1308082, SBBI12 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prelid1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lipid transporter
- phospholipid transporter
- protein binding
- transporter
- PRELI-like family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
- STAT6
- phosphatidic acid
- endopeptidase
- reactive oxygen species
role in cell
- expression in
- production in
- apoptosis
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial intermembrane space
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prelid1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of phospholipid transport
- regulation of T cell differentiation
- negative regulation of mitochondrial membrane potential
- regulation of membrane lipid distribution
- negative regulation of release of cytochrome c from mitochondria
- regulation of mitochondrial membrane potential
- negative regulation of apoptotic process
- apoptotic process
- phospholipid transport
- positive regulation of T cell apoptotic process
- positive regulation of endopeptidase activity
Cellular Component
Where in the cell the gene product is active
- mitochondrial intermembrane space
- mitochondrion
- macromolecular complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding