Retnlb Gene Summary [Mouse]
Predicted to enable hormone activity. Acts upstream of or within response to bacterium. Located in extracellular region. Is expressed in several structures, including brown fat; genitourinary system; intestine; liver; and spleen. Orthologous to human RETNLB (resistin like beta). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Retnlb |
| Official Name | resistin like beta [Source:MGI Symbol;Acc:MGI:1888505] |
| Ensembl ID | ENSMUSG00000022650 |
| Bio databases IDs | |
| Aliases | resistin like beta |
| Synonyms | 9030012B21Rik, CCRG, Fizz, FIZZ1, FIZZ2, HXCP2, RELMb, RELM beta, RELM-β, Resistin Beta, resistin like beta, resistin like β, Resistin β, RETNL2, XCP2, Xcp3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Retnlb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- resistin-like molecule (RELM) hormone family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- hyperlipidemia
- pulmonary fibrosis
- dextran sodium sulfate-induced colitis
- idiopathic pulmonary fibrosis
- insulin resistance
- weight gain
- hyperglycemia
- hepatic steatosis
- colitis
role in cell
- expression in
- number
- function
- recruitment
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- detergent resistant lipid raft fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Retnlb gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- epithelial cell proliferation
- signal transduction
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- hormone activity