Taf11 Gene Summary [Mouse]
Enables DNA binding activity. Predicted to be involved in positive regulation by host of viral transcription; positive regulation of transcription initiation by RNA polymerase II; and transcription by RNA polymerase II. Located in nucleus. Is expressed in brain; genitourinary system; heart; and tail. Orthologous to human TAF11 (TATA-box binding protein associated factor 11). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Taf11 |
| Official Name | TATA-box binding protein associated factor 11 [Source:MGI Symbol;Acc:MGI:1916026] |
| Ensembl ID | ENSMUSG00000024218 |
| Bio databases IDs | |
| Aliases | TATA-box binding protein associated factor 11 |
| Synonyms | 1110038O14Rik, MGC:15243, PRO2134, PRO214, TAF2I, TAFII28, TATA-box binding protein associated factor 11 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Taf11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone-fold domain
- histone fold domain (HFD) superfamily
- transcription regulator
- transcription co-activator
- vitamin D receptor binding
- protein binding
- thyroid hormone receptor binding
- TATA-binding protein binding
- DNA binding
Pathways
Biological processes and signaling networks where the Taf11 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Golgi Apparatus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Taf11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation by host of viral transcription
- mRNA transcription from RNA polymerase II promoter
- RNA polymerase II transcriptional preinitiation complex assembly
- positive regulation of transcription initiation from RNA polymerase II promoter
- transcription from RNA polymerase II promoter
- transcription initiation from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- transcription factor TFIID complex
- Golgi apparatus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription coactivator activity
- protein heterodimerization activity
- general RNA polymerase II transcription factor activity
- vitamin D receptor binding
- TBP-class protein binding
- thyroid hormone receptor binding