Actr3

Predicted to enable ATPase binding activity and actin binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to contribute to actin filament binding activity. Acts upstream of or within several processes, including cellular response to type II interferon; meiotic chromosome movement towards spindle pole; and meiotic cytokinesis. Located in brush border; cell-cell junction; and lamellipodium. Is expressed in several structures, including alimentary system; cerebral cortex; cochlea; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in opisthorchiasis. Orthologous to human ACTR3 (actin related protein 3). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Actr3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Actr3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Actr3 gene, providing context for its role in the cell.