Cd6 Gene Summary [Mouse]
Predicted to enable several functions, including identical protein binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Predicted to be involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; lipopolysaccharide-mediated signaling pathway; and positive regulation of macromolecule metabolic process. Predicted to be located in cell surface and immunological synapse. Predicted to be part of T cell receptor complex. Orthologous to human CD6 (CD6 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cd6 |
| Official Name | CD6 antigen [Source:MGI Symbol;Acc:MGI:103566] |
| Ensembl ID | ENSMUSG00000024670 |
| Bio databases IDs | |
| Aliases | CD6 antigen |
| Synonyms | CD6 antigen, CD6 molecule, LOC100911366, OX52, TP120 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular domain
- Scavenger receptor cysteine-rich domain
- binding protein
- protein kinase binding
- cytoplasmic domain
- ectodomain
- protein binding
- identical protein binding
- lipopolysaccharide binding
- transmembrane receptor
- Scavenger receptor Cys-rich
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- experimental autoimmune encephalomyelitis
- rheumatoid arthritis
- ulcerative colitis
- chronic periodontal disease
- collagen-induced arthritis
- inflammatory bowel disease
- diabetic nephropathy
- Rett syndrome
- primary Sjögren syndrome
- multiple sclerosis
role in cell
- production in
- apoptosis
- proliferation
- activation
- number
- binding in
- binding
- formation
- function
- formation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
- immunological synapses
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cd6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acute inflammatory response to antigenic stimulus
- innate immune response
- positive regulation of protein phosphorylation
- heterophilic cell-cell adhesion
- lipopolysaccharide-mediated signaling pathway
- adaptive immune response
- response to lipopolysaccharide
- positive regulation of T cell proliferation
- positive regulation of cytokine production involved in inflammatory response
- immunological synapse formation
Cellular Component
Where in the cell the gene product is active
- T cell receptor complex
- extracellular region
- plasma membrane
- cell surface
- immunological synapse
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- identical protein binding
- protein binding
- lipoteichoic acid binding
- lipopolysaccharide binding