Cst6

Acts upstream of or within epidermis development. Located in cornified envelope. Is expressed in several structures, including alimentary system; placenta; respiratory system; sensory organ; and skin. Used to study autosomal recessive congenital ichthyosis 4B. Human ortholog(s) of this gene implicated in ectodermal dysplasia 15. Orthologous to human CST6 (cystatin E/M). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cst6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Cst6 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cst6 gene, providing context for its role in the cell.