Tesmin Gene Summary [Mouse]

Involved in male meiotic nuclear division and spermatogenesis. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including adrenal gland; gonad; heart; liver; and lung. Orthologous to human TESMIN (testis expressed metallothionein like protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Tesmin
Official Name
testis expressed metallothionein like [Source:MGI Symbol;Acc:MGI:1340029]
Ensembl ID
ENSMUSG00000024905
Bio databases IDs NCBI: 17771 Ensembl: ENSMUSG00000024905
Aliases testis expressed metallothionein like
Synonyms CXCDC2, MTL5, MTLT, testis expressed metallothionein like, testis expressed metallothionein like protein
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tesmin often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Tesmin/TSO1-like CXC domain, cysteine-rich domain
  • DNA-binding cysteine-rich domain of male-specific lethal 2 and related proteins

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung adenocarcinoma
  • lung adenocarcinoma formation
regulated by
  • dexamethasone
  • ritonavir
  • ESR1
  • cisplatin
  • rifampin
  • troglitazone
  • NR3C1
  • STK11
  • MEIOSIN/STRA8
role in cell
  • meiosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tesmin gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spermatogenesis
  • male meiosis
  • cell differentiation
  • response to metal ion
  • regulation of transcription, DNA-dependent
  • cellular cation homeostasis

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • male germ cell nucleus

Molecular Function

What the gene product does at the molecular level
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.