Mcat Gene Summary [Mouse]
Predicted to enable [acyl-carrier-protein] S-malonyltransferase activity. Predicted to be involved in fatty acid biosynthetic process and mitochondrial small ribosomal subunit assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human MCAT (malonyl-CoA-acyl carrier protein transacylase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mcat |
| Official Name | malonyl CoA:ACP acyltransferase (mitochondrial) [Source:MGI Symbol;Acc:MGI:2388651] |
| Ensembl ID | ENSMUSG00000048755 |
| Bio databases IDs | |
| Aliases | malonyl CoA:ACP acyltransferase (mitochondrial) |
| Synonyms | fabD, FASN2C, LOC632398, malonyl CoA:ACP acyltransferase (mitochondrial), malonyl-CoA-acyl carrier protein transacylase, MCT, MCT1, MT, NET62, OPA15, RGD1306698 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mcat often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- [acyl-carrier-protein] S-malonyltransferase
- malonyl CoA-acyl carrier protein transacylase
- Acyl transferase domain
- enzyme
- malonate decarboxylase, epsilon subunit
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mcat gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fatty acid beta-oxidation
- fatty acid biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- [acyl-carrier-protein] S-malonyltransferase activity
- RNA binding