Rab40c Gene Summary [Mouse]
Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in exocytosis. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in endosome; plasma membrane; and synaptic vesicle. Predicted to colocalize with Golgi apparatus and lipid droplet. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system gland. Orthologous to human RAB40C (RAB40C, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Rab40c |
| Official Name | Rab40C, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:2183454] |
| Ensembl ID | ENSMUSG00000025730 |
| Bio databases IDs | |
| Aliases | Rab40C, member RAS oncogene family |
| Synonyms | RAB40, RAB40C, member RAS oncogene family, RAR3, RARL, RASL8C |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rab40c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- SOCS box
- small GTP-binding protein domain
- GDP binding
- Ras family
- Rab subfamily of small GTPases
- SOCS
- Ras of Complex, Roc, domain of DAPkinase
- Rho (Ras homology) subfamily of Ras-like small GTPases
- Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases
- P-loop containing Nucleoside Triphosphate Hydrolases
- Ras subfamily of RAS small GTPases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- perinuclear region
- Plasma Membrane
- Golgi Apparatus
- lipid droplets
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rab40c gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein secretion
- exocytosis
- intracellular signal transduction
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- lipid particle
- endosome
- perinuclear region of cytoplasm
- synaptic vesicle
- Golgi apparatus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- GTP binding
- GTPase activity
- GDP binding