Utp11 Gene Summary [Mouse]
Predicted to be involved in nervous system development; positive regulation of apoptotic process; and ribosomal small subunit biogenesis. Predicted to be located in cytoplasm and extracellular space. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in cerebral cortex ventricular layer; trigeminal ganglion; and vertebral axis musculature. Orthologous to human UTP11 (UTP11 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Utp11 |
| Official Name | UTP11 small subunit processome component [Source:MGI Symbol;Acc:MGI:1914455] |
| Ensembl ID | ENSMUSG00000028907 |
| Bio databases IDs | |
| Aliases | UTP11 small subunit processome component |
| Synonyms | 2700082D03Rik, CGI-94, LOC51118, RGD1559610, UTP11L, UTP11 small subunit processome component, UTP11, small subunit processome component |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Utp11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Utp11 protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- breast cancer
- liver cancer
- epithelial cancer
- organismal death
- colorectal cancer
- hepatocellular carcinoma
- immunodeficiency
- infection by vesicular stomatitis virus
role in cell
- ferroptosis
- cell viability
- expression in
- growth
- apoptosis
- processing in
- ubiquitination in
- synthesis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- pre-ribosome
- Cytoplasm
- Extracellular Space
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Utp11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosomal small subunit biogenesis
- positive regulation of apoptotic process
- nervous system development
- rRNA processing
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- extracellular space
- cytoplasm
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding