Tinagl1 Gene Summary [Mouse]
Enables laminin binding activity. Predicted to be involved in proteolysis. Located in cytoplasm. Is expressed in several structures, including adrenal gland; blastocyst; brain ventricle; early embryo; and submandibular gland primordium. Orthologous to human TINAGL1 (tubulointerstitial nephritis antigen like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Tinagl1 |
| Official Name | tubulointerstitial nephritis antigen-like 1 [Source:MGI Symbol;Acc:MGI:2137617] |
| Ensembl ID | ENSMUSG00000028776 |
| Bio databases IDs | |
| Aliases | tubulointerstitial nephritis antigen-like 1 |
| Synonyms | 1110021J17Rik, ARG1, AZ-1, Gis5, LCN7, LIECG3, Lipocalin 7, OLRG-2, pp6614, TARP, TINAGL, TINAGRP, tubulointerstitial nephritis antigen-like 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tinagl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- laminin binding
- Peptidase_C1
- protein binding
- Somatomedin B domain
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- extracellular vesicles
- Cytoplasm
- exosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tinagl1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- endosomal transport
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
- cytoplasm
- extracellular region
- lysosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- cysteine-type peptidase activity
- extracellular matrix structural constituent
- laminin binding