Pzp Gene Summary [Mouse]
Enables endopeptidase inhibitor activity. Acts upstream of or within embryo implantation. Located in collagen-containing extracellular matrix. Is expressed in liver and liver lobe. [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pzp |
| Official Name | PZP, alpha-2-macroglobulin like [Source:MGI Symbol;Acc:MGI:87854] |
| Ensembl ID | ENSMUSG00000030359 |
| Bio databases IDs | |
| Aliases | PZP, alpha-2-macroglobulin like |
| Synonyms | A1m, A2m, Alpha 1 Macroglobulin, MAM, pregnancy-zone protein, PZP, alpha-2-macroglobulin like, PZP, α-2-macroglobulin like, α 1 Macroglobulin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pzp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- endopeptidase inhibitor
- Alpha-2-macroglobulin bait region domain
- ISOPREN_C2_like
- binding protein
- Macroglobulin domain MG4
- A-macroglobulin TED domain
- A-macroglobulin receptor binding domain
- growth factor binding
- Alpha-2-macroglobulin family
- MG2 domain
- Macroglobulin domain MG3
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space