Chst15 Gene Summary [Mouse]
Predicted to enable 3'-phosphoadenosine 5'-phosphosulfate binding activity and N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity. Predicted to be involved in hexose biosynthetic process. Predicted to be located in Golgi membrane. Is expressed in several structures, including alimentary system; appendicular skeleton; central nervous system; genitourinary system; and sensory organ. Orthologous to human CHST15 (carbohydrate sulfotransferase 15). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Chst15 |
| Official Name | carbohydrate sulfotransferase 15 [Source:MGI Symbol;Acc:MGI:1924840] |
| Ensembl ID | ENSMUSG00000030930 |
| Bio databases IDs | |
| Aliases | carbohydrate sulfotransferase 15 |
| Synonyms | 4631426J05Rik, BRAG, carbohydrate sulfotransferase 15, carbohydrate sulphotransferase 15, GALNAC4S-6ST, GalNAcS-6ST, MAd5, mKIAA0598 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Chst15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase
- enzyme
- protein binding
- 3'-phosphoadenosine 5'-phosphosulfate binding
- Sulfotransferase family
Pathways
Biological processes and signaling networks where the Chst15 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- familial myeloproliferative neoplasm
- myeloproliferative disorder
- bone marrow cancer
- hereditary cancer
- lung adenocarcinoma
- lung adenocarcinoma formation
- Waldenström macroglobulinemia
- gastroesophageal reflux
role in cell
- number
- proliferation
- expression in
- abnormal morphology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- intracellular space
- stereocilia
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Chst15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chondroitin sulfate biosynthetic process
- hexose biosynthetic process
Cellular Component
Where in the cell the gene product is active
- membrane
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity
- 3'-phosphoadenosine 5'-phosphosulfate binding