Cngb1

Enables cyclic nucleotide-activated monoatomic ion channel activity. Acts upstream of or within several processes, including photoreceptor cell maintenance; photoreceptor cell outer segment organization; and sensory perception of smell. Located in membrane and photoreceptor outer segment. Is expressed in several structures, including head mesenchyme; incisor; limb; sensory organ; and skeleton. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 45. Orthologous to human CNGB1 (cyclic nucleotide gated channel subunit beta 1). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cngb1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Cngb1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cngb1 gene, providing context for its role in the cell.