Map3k13

Enables protein serine/threonine kinase activator activity and protein serine/threonine kinase activity. Involved in several processes, including positive regulation of JUN kinase activity; positive regulation of branching morphogenesis of a nerve; and positive regulation of cell projection organization. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in diencephalon lateral wall mantle layer; dorsal grey horn; late tubule; midbrain mantle layer; and ureter. Orthologous to human MAP3K13 (mitogen-activated protein kinase kinase kinase 13). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Map3k13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Map3k13 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Map3k13 gene, providing context for its role in the cell.