Galm Gene Summary [Mouse]
Predicted to enable aldose 1-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose, Leloir pathway and glucose metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; forebrain; heart; liver; and sensory organ. Human ortholog(s) of this gene implicated in galactosemia 4. Orthologous to human GALM (galactose mutarotase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Galm |
| Official Name | galactose mutarotase [Source:MGI Symbol;Acc:MGI:2442420] |
| Ensembl ID | ENSMUSG00000035473 |
| Bio databases IDs | |
| Aliases | galactose mutarotase |
| Synonyms | A530057M15RIK, aldose 1-epimerase, BLOCK25, GALAC4, galactose mutarotase, GLAT, HEL-S-63p, IBD1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Galm often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- aldose 1-epimerase superfamily
- aldose 1-epimerase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Galm gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- carbohydrate metabolic process
- galactose catabolic process via UDP-galactose
- galactose metabolic process
- glucose metabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein homodimerization activity
- aldose 1-epimerase activity
- carbohydrate binding