Dnajc12 Gene Summary [Mouse]
Predicted to be active in cytoplasm. Is expressed in brain; gut; liver lobe; and lung. Orthologous to human DNAJC12 (DnaJ heat shock protein family (Hsp40) member C12). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dnajc12 |
| Official Name | DnaJ heat shock protein family (Hsp40) member C12 [Source:MGI Symbol;Acc:MGI:1353428] |
| Ensembl ID | ENSMUSG00000036764 |
| Bio databases IDs | |
| Aliases | DnaJ heat shock protein family (Hsp40) member C12 |
| Synonyms | DnaJ heat shock protein family (Hsp40) member C12, HPANBH4, JDP1, mJDP1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dnajc12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DnaJ domain
- DnaJ
- DnaJ molecular chaperone homology domain
- protein binding
Pathways
Biological processes and signaling networks where the Dnajc12 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- renal clear cell adenocarcinoma
- hereditary disorder
- non-BH4-deficient mild hyperphenylalaninemia
- liver cancer
- hepatocellular carcinoma
- lung adenocarcinoma
- lung adenocarcinoma formation
- atrial fibrillation
- major depression
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dnajc12 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding