Mybpc2 Gene Summary [Mouse]
Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in sarcomere organization. Predicted to act upstream of or within muscle contraction. Predicted to be located in cytoskeleton. Predicted to be active in M band. Is expressed in diaphragm; extensor digitorum longus; hindlimb; rectus femoris; and soleus. Orthologous to human MYBPC2 (myosin binding protein C2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mybpc2 |
| Official Name | myosin binding protein C, fast-type [Source:MGI Symbol;Acc:MGI:1336170] |
| Ensembl ID | ENSMUSG00000038670 |
| Bio databases IDs | |
| Aliases | myosin binding protein C, fast-type |
| Synonyms | fsMyBP-C, Mhc-F, MYBPC, MYBPCF, MyBP-C Fast, myosin binding protein C2, myosin binding protein C, fast-type |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mybpc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tri-helix bundle domain
- structural constituent of muscle
- structural constituent of cytoskeleton
- FN3
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- protein binding
- Fibronectin type 3 domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Crohn disease
- Alzheimer disease
- non-insulin-dependent diabetes mellitus
- polycystic ovary syndrome
- colon cancer
- myositis
- COVID-19
- centronuclear myopathy
- papillary thyroid carcinoma
- papillary thyroid cancer
role in cell
- abnormal morphology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoskeleton
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mybpc2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sarcomere organization
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- myosin filament
- cytosol
- M band
Molecular Function
What the gene product does at the molecular level
- structural constituent of muscle
- protein binding
- actin binding