Abcf1 Gene Summary [Mouse]
Predicted to enable ATP binding activity; ribosome binding activity; and translation activator activity. Predicted to be involved in positive regulation of translation and translational initiation. Predicted to be located in cytosol; nucleus; and ribosome. Is expressed in several structures, including eye; genitourinary system; hemolymphoid system; lung; and nervous system. Orthologous to human ABCF1 (ATP binding cassette subfamily F member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Abcf1 |
| Official Name | ATP-binding cassette, sub-family F (GCN20), member 1 [Source:MGI Symbol;Acc:MGI:1351658] |
| Ensembl ID | ENSMUSG00000038762 |
| Bio databases IDs | |
| Aliases | ATP-binding cassette, sub-family F (GCN20), member 1 |
| Synonyms | ABC27, ABC50, ATP binding cassette subfamily F member 1, ATP-binding cassette, sub-family F member 1, AU041969, D17Wsu166e, GCN20 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Abcf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- nucleic acid binding translation factor
- FeS assembly ATPase SufC
- proposed F420-0 ABC transporter, ATP-binding protein
- walker type B motif
- translation activator
- phosphonate ABC transporter, ATP-binding protein
- walker type A motif
- ATP binding
- protein binding
- cell division ATP-binding protein FtsE
- heme ABC exporter, ATP-binding protein CcmA
- nucleotide-binding domain
- ATP-binding cassette protein, ChvD family
- ribosome binding
- methyl coenzyme M reductase system, component A2
- phosphonate C-P lyase system protein PhnL
- nickel import ATP-binding protein NikE
- ABC transporter
- P-loop containing Nucleoside Triphosphate Hydrolases
- transporter
- ATPases associated with a variety of cellular activities
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- Nucleus
- cytosol
- nucleoplasm
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Abcf1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- translation
Cellular Component
Where in the cell the gene product is active
- nuclear envelope
- membrane
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- protein binding
- RNA binding
- translation factor activity, nucleic acid binding