Tasp1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity and threonine-type endopeptidase activity. Predicted to be involved in positive regulation of DNA-templated transcription; protein maturation; and proteolysis. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in brain ventricle; branchial arch; head; and limb bud. Orthologous to human TASP1 (taspase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tasp1 |
| Official Name | taspase, threonine aspartase 1 [Source:MGI Symbol;Acc:MGI:1923062] |
| Ensembl ID | ENSMUSG00000039033 |
| Bio databases IDs | |
| Aliases | taspase, threonine aspartase 1 |
| Synonyms | 4930485D02Rik, C20orf13, dJ585I14.2, LOC105372536, LOC105372538, RGD1308591, SULEHS, TASPASE1, taspase, threonine aspartase 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tasp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- L-Asparaginase type 2-like enzymes of the NTN-hydrolase superfamily
- threonine endopeptidase
- peptidase
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- azoospermia
- glioblastoma
- glioblastoma cancer
- chronic obstructive pulmonary disease
- hypoplasia
- Suleiman-El-Hattab syndrome
- global developmental delay
role in cell
- binding in
- binding
- expression in
- apoptosis
- cell death
- proliferation
- molecular cleavage in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tasp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- proteolysis
- protein maturation
- regulation of gene expression, epigenetic
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- threonine-type endopeptidase activity