Dok4

Acts upstream of or within cell surface receptor protein tyrosine kinase signaling pathway; nervous system development; and positive regulation of MAPK cascade. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; dorsal root ganglion; heart; retina; and spleen primordium. Orthologous to human DOK4 (docking protein 4). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dok4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Dok4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Dok4 gene, providing context for its role in the cell.