Tiprl Gene Summary [Mouse]
Predicted to enable protein phosphatase activator activity. Predicted to be involved in DNA damage checkpoint signaling and TOR signaling. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and immune system. Orthologous to human TIPRL (TOR signaling pathway regulator). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tiprl |
| Official Name | TIP41, TOR signalling pathway regulator-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1915087] |
| Ensembl ID | ENSMUSG00000040843 |
| Bio databases IDs | |
| Aliases | TIP41, TOR signalling pathway regulator-like (S. cerevisiae) |
| Synonyms | 1810011K17Rik, LOC686733, RGD1310442, TAB4, TIP, TIP41, TIP41, TOR signalling pathway regulator-like (S. cerevisiae), TIPRL1, TOR signaling pathway regulator |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tiprl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase inhibitor activity
- TIP41-like family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tiprl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA damage checkpoint
- negative regulation of phosphoprotein phosphatase activity
- TOR signaling cascade
- regulation of phosphoprotein phosphatase activity
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding