Ppp4r2 Gene Summary [Mouse]
Predicted to enable protein phosphatase regulator activity and protein-macromolecule adaptor activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in cytoplasm and nucleus. Part of protein phosphatase 4 complex. Is expressed in several structures, including genitourinary system; gut; immune system; liver and biliary system; and nervous system. Orthologous to human PPP4R2 (protein phosphatase 4 regulatory subunit 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppp4r2 |
| Official Name | protein phosphatase 4, regulatory subunit 2 [Source:MGI Symbol;Acc:MGI:3027896] |
| Ensembl ID | ENSMUSG00000052144 |
| Bio databases IDs | |
| Aliases | protein phosphatase 4, regulatory subunit 2 |
| Synonyms | C230060M08RIK, PP4R2, protein phosphatase 4 regulatory subunit 2, protein phosphatase 4, regulatory subunit 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppp4r2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- protein phosphatase regulator
- PPP4R2
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- centrosome
- nucleoplasm
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppp4r2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein modification process
- RNA splicing
- regulation of double-strand break repair
- regulation of double-strand break repair via homologous recombination
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cytoplasm
- protein phosphatase 4 complex
- chromatin
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein binding, bridging
- protein phosphatase regulator activity