Gpr156 Gene Summary [Mouse]

Predicted to enable G protein-coupled GABA receptor activity. Involved in stereocilium bundle organization. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; mammary gland; and trachea. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness. Orthologous to human GPR156 (G protein-coupled receptor 156). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gpr156
Official Name
G protein-coupled receptor 156 [Source:MGI Symbol;Acc:MGI:2653880]
Ensembl ID
ENSMUSG00000046961
Bio databases IDs NCBI: 239845 Ensembl: ENSMUSG00000046961
Aliases G protein-coupled receptor 156
Synonyms DFNB121, GABABL, G protein-coupled receptor 156, LOC103693583, PGR28
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr156 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • 7 transmembrane sweet-taste receptor of 3 GCPR
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Gpr156 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • autosomal recessive deafness type 121
  • autosomal recessive deafness
regulated by
role in cell
  • cisplatin sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr156 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • gamma-aminobutyric acid signaling pathway

Cellular Component

Where in the cell the gene product is active
  • G-protein coupled receptor heterodimeric complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled GABA receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.