Cdh19 Gene Summary [Mouse]

Predicted to enable beta-catenin binding activity and cadherin binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and cell-cell junction organization. Predicted to be part of catenin complex. Predicted to be active in adherens junction. Is expressed in several structures, including alimentary system; ear; genitourinary system; integumental system; and nervous system. Orthologous to human CDH19 (cadherin 19). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cdh19
Official Name
cadherin 19, type 2 [Source:MGI Symbol;Acc:MGI:3588198]
Ensembl ID
ENSMUSG00000047216
Bio databases IDs NCBI: 227485 Ensembl: ENSMUSG00000047216
Aliases cadherin 19, type 2
Synonyms cadherin 19, cadherin 19, type 2, CDH7, CDH7L2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cdh19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cadherin, Y-type LIR-motif
  • Cadherin repeat-like domain

Pathways

Biological processes and signaling networks where the Cdh19 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • glomerulonephritis
  • cholesteatoma
regulated by
  • estrogen receptor
  • CDH19
  • ZC3H12A:CDH19 gene
  • mir-802
  • TGFB1
  • SOX10:CDH19 gene
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cdh19 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • calcium-dependent cell-cell adhesion
  • cell-cell junction assembly
  • adherens junction organization
  • multicellular organismal development
  • cell morphogenesis
  • cell-cell adhesion mediated by cadherin
  • homophilic cell adhesion
  • cell migration

Cellular Component

Where in the cell the gene product is active
  • adherens junction
  • catenin complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • calcium ion binding
  • cadherin binding
  • beta-catenin binding

Gene-Specific Assays for Results You Can Trust

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