Prrg1 Gene Summary [Mouse]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in blood coagulation. Predicted to be active in extracellular space. Orthologous to human PRRG1 (proline rich and Gla domain 1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Prrg1
Official Name
proline rich Gla (G-carboxyglutamic acid) 1 [Source:MGI Symbol;Acc:MGI:1917364]
Ensembl ID
ENSMUSG00000047996
Bio databases IDs NCBI: 546336 Ensembl: ENSMUSG00000047996
Aliases proline rich Gla (G-carboxyglutamic acid) 1
Synonyms 2010007L08RIK, PRGP1, proline rich and Gla domain 1, proline rich Gla (G-carboxyglutamic acid) 1, RGD1561320, TMG1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prrg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • preeclampsia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Prrg1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.