Chd9 Gene Summary [Mouse]
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and DNA helicase activity. Predicted to be involved in chromatin organization. Predicted to be located in cytosol and nucleoplasm. Is expressed in bone; endochondral bone; and periosteum. Orthologous to human CHD9 (chromodomain helicase DNA binding protein 9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Chd9 |
| Official Name | chromodomain helicase DNA binding protein 9 [Source:MGI Symbol;Acc:MGI:1924001] |
| Ensembl ID | ENSMUSG00000056608 |
| Bio databases IDs | |
| Aliases | chromodomain helicase DNA binding protein 9 |
| Synonyms | 1810014J18RIK, 9030205D12RIK, A330063D19Rik, AD-013, BC022889, chromodomain helicase DNA binding protein 9, CReMM, KISH2, LOC680231, mKIAA0308, PRIC320 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Chd9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Chromatin organization modifier domain
- DEAD/DEAH box helicase
- SNF2-related domain
- helicase superfamily c-terminal domain
- protein binding
- Helicase conserved C-terminal domain
- CHROMO (CHRromatin Organization Modifier) domains and chromo shadow domains
- BRK domain
- Type III restriction enzyme, res subunit
- N-terminal helicase domain of the DEAD-box helicase superfamily
- Class II histone deacetylase complex subunits 2 and 3
- DEAD-like helicases superfamily
- Chromo (CHRromatin organization MOdifier) domain
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- tumorigenesis
- coronary artery disease
- systemic lupus erythematosus
- diabetic peripheral neuropathy
- venous thromboembolism
- ischemic stroke
- pelvic organ prolapse
- ocular hypertension
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Chd9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromatin remodeling
Cellular Component
Where in the cell the gene product is active
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- DNA binding
- helicase activity