Tmed9 Gene Summary [Mouse]
Predicted to enable syntaxin binding activity. Predicted to be involved in several processes, including Golgi organization; Golgi vesicle transport; and intracellular protein transport. Located in synaptic vesicle. Is expressed in embryo. Orthologous to human TMED9 (transmembrane p24 trafficking protein 9). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmed9 |
| Official Name | transmembrane p24 trafficking protein 9 [Source:MGI Symbol;Acc:MGI:1914761] |
| Ensembl ID | ENSMUSG00000058569 |
| Bio databases IDs | |
| Aliases | transmembrane p24 trafficking protein 9 |
| Synonyms | 2400003B06Rik, GMP25, GP25L2, HSGP25L2G, p24a2, p24 alpha2, p25, RGD1307627, transmembrane p24 trafficking protein 9 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmed9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytoplasmic domain
- protein binding
- cytosolic tail domain
- emp24/gp25L/p24 family/GOLD
- transporter
- syntaxin binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi-enriched fraction
- membrane fraction
- pH resistant lipid raft fraction
- cellular membrane
- Golgi Apparatus
- Endoplasmic Reticulum
- Mitochondria
- ER-to-Golgi intermediate compartment
- endoplasmic reticulum membrane
- Golgi membrane
- nuclear envelope
- synaptic vesicles
- transport vesicles
- smooth endoplasmatic reticulum
- rough endoplasmatic reticulum
- cis Golgi cisternae
- detergent-soluble fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmed9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ER to Golgi vesicle-mediated transport
- protein exit from endoplasmic reticulum
- Golgi organization
- positive regulation of organelle organization
- COPI coating of Golgi vesicle
- early endosome to Golgi transport
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- extracellular vesicular exosome
- synaptic vesicle
- trans-Golgi network transport vesicle
- ER to Golgi transport vesicle
- Golgi apparatus
- endoplasmic reticulum
- Golgi membrane
- endoplasmic reticulum-Golgi intermediate compartment
- transport vesicle
- endoplasmic reticulum-Golgi intermediate compartment membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- syntaxin binding
- cargo receptor activity