Kalrn

Predicted to enable enzyme binding activity and guanyl-nucleotide exchange factor activity. Acts upstream of or within several processes, including learning or memory; maternal behavior; and maternal process involved in parturition. Predicted to be located in several cellular components, including neuronal cell body; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be active in several cellular components, including glutamatergic synapse; postsynaptic density; and presynapse. Predicted to be extrinsic component of membrane. Is expressed in cerebral cortex ventricular layer; cortical plate; dorsal root ganglion; and spinal cord. Human ortholog(s) of this gene implicated in cerebral atherosclerosis; cerebral infarction; and coronary artery disease. Orthologous to human KALRN (kalirin RhoGEF kinase). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kalrn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Kalrn gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Kalrn gene, providing context for its role in the cell.