Ces3b Gene Summary [Mouse]

Predicted to enable carboxylesterase activity. Predicted to be located in endoplasmic reticulum lumen. Orthologous to human CES3 (carboxylesterase 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Ces3b
Official Name
carboxylesterase 3B [Source:MGI Symbol;Acc:MGI:3644960]
Ensembl ID
ENSMUSG00000062181
Bio databases IDs NCBI: 13909 Ensembl: ENSMUSG00000062181
Aliases carboxylesterase 3B
Synonyms carboxylesterase 3, carboxylesterase 3a, carboxylesterase 3B, Ces31L, Ces3a, Ces3b, Ces3L, Ces3-ps1, EG13909, ES31, ES31L, FLJ21736, Gm4738, LOC100363706
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ces3b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • carboxylic ester hydrolase
  • Carboxylesterase family
  • alpha/beta hydrolases
  • enzyme

Pathways

Biological processes and signaling networks where the Ces3b gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • cholesterol
  • NFKB2
  • cholesterol ester
  • SN-38
  • 7-ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecine
  • xenobiotic
  • bile acid
  • irinotecan
  • sterol

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol
  • endoplasmic reticulum lumen
  • microsomal membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ces3b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • low-density lipoprotein particle clearance
  • xenobiotic metabolic process

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum lumen
  • extracellular vesicular exosome
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • carboxylic ester hydrolase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.