Tubg1

Predicted to enable GTP binding activity; identical protein binding activity; and microtubule nucleator activity. Involved in meiotic spindle organization. Located in several cellular components, including condensed nuclear chromosome; microtubule cytoskeleton; and non-motile cilium. Is expressed in several structures, including central nervous system; eye; head mesenchyme; heart; and respiratory system. Used to study complex cortical dysplasia with other brain malformations 4. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 4; inclusion body myositis; and muscular disease. Orthologous to human TUBG1 (tubulin gamma 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tubg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Tubg1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tubg1 gene, providing context for its role in the cell.