Scgb3a1 Gene Summary [Mouse]
This gene encodes a small secreted protein that may function in the inhibition of cell growth. Expression of the related gene in humans is downregulated via DNA methylation in breast cancers and other tumor types. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
Details
| Type | Protein Coding |
| Official Symbol | Scgb3a1 |
| Official Name | secretoglobin, family 3A, member 1 [Source:MGI Symbol;Acc:MGI:1915912] |
| Ensembl ID | ENSMUSG00000064057 |
| Bio databases IDs | |
| Aliases | secretoglobin, family 3A, member 1 |
| Synonyms | HIN-1, LU105, LuLeu2, PnSP-2, secretoglobin, secretoglobin family 3A member 1, secretoglobin, family 3A, member 1, UGRP2, Utgrp2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Scgb3a1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Secretoglobin 3A
- protein binding
- cytokine
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell surface
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Scgb3a1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- negative regulation of cell growth
- regulation of cell proliferation
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
Molecular Function
What the gene product does at the molecular level
- protein binding
- cytokine activity