Vps37b

Predicted to enable calcium-dependent protein binding activity. Predicted to be involved in several processes, including positive regulation of viral budding via host ESCRT complex; protein targeting; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be located in endosome membrane; midbody; and plasma membrane. Predicted to be part of ESCRT I complex. Is expressed in several structures, including central nervous system; cranium; and retina. Orthologous to human VPS37B (VPS37B subunit of ESCRT-I). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Vps37b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Vps37b gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Vps37b gene, providing context for its role in the cell.