Urm1 Gene Summary [Mouse]

Predicted to enable protein tag activity and sulfur carrier activity. Predicted to be involved in protein urmylation; tRNA thio-modification; and tRNA wobble uridine modification. Predicted to be located in cytosol. Predicted to be active in nucleus. Is expressed in mandible; nervous system; and neural retina. Orthologous to human URM1 (ubiquitin related modifier 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Urm1
Official Name
ubiquitin related modifier 1 [Source:MGI Symbol;Acc:MGI:1915455]
Ensembl ID
ENSMUSG00000069020
Bio databases IDs NCBI: 68205 Ensembl: ENSMUSG00000069020
Aliases ubiquitin related modifier 1
Synonyms 2900073H19Rik, C9orf74, RGD1306599, ubiquitin related modifier 1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Urm1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ubl1_cv_Nsp3_N-like
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • expression in
  • migration
  • invasion by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Urm1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • tRNA wobble uridine modification
  • protein urmylation
  • tRNA thio-modification

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • protein tag
  • sulfur carrier activity

Gene-Specific Assays for Results You Can Trust

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