URM1 Gene Summary [Human]
Enables sulfur carrier activity. Involved in tRNA thio-modification and tRNA wobble uridine modification. Predicted to be located in cytosol. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | URM1 |
| Official Name | ubiquitin related modifier 1 [Source:HGNC Symbol;Acc:HGNC:28378] |
| Ensembl ID | ENSG00000167118 |
| Bio databases IDs | |
| Aliases | ubiquitin related modifier 1 |
| Synonyms | 2900073H19Rik, C9orf74, RGD1306599, ubiquitin related modifier 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human URM1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubl1_cv_Nsp3_N-like
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human URM1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tRNA wobble uridine modification
- protein urmylation
- tRNA thio-modification
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein tag
- sulfur carrier activity