Dazap1 Gene Summary [Mouse]
Enables RNA stem-loop binding activity. Acts upstream of or within several processes, including fibroblast proliferation; maternal placenta development; and positive regulation of mRNA splicing, via spliceosome. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human DAZAP1 (DAZ associated protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dazap1 |
| Official Name | DAZ associated protein 1 [Source:MGI Symbol;Acc:MGI:1917498] |
| Ensembl ID | ENSMUSG00000069565 |
| Bio databases IDs | |
| Aliases | DAZ associated protein 1 |
| Synonyms | 2410042M16Rik, DAZ associated protein 1, mPrrp |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dazap1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- protein binding
- single-stranded RNA binding
- RNA binding
- poly(U) binding protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- growth failure
- organismal death
- leukemic non-nodal mantle cell lymphoma
- idiopathic pulmonary fibrosis
- conventional mantle cell lymphoma
regulates
role in cell
- expression in
- proliferation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nucleoplasm
- paraspeckle-like structures
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dazap1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fibroblast proliferation
- positive regulation of nuclear mRNA splicing, via spliceosome
- spermatogenesis
- cell differentiation
- maternal placenta development
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- macromolecular complex
- male germ cell nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- poly(G) RNA binding
- RNA stem-loop binding
- poly(U) RNA binding
- mRNA 3'-UTR binding