Ccnb1ip1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Involved in chiasma assembly. Acts upstream of or within blastocyst formation and spermatid development. Located in condensed nuclear chromosome. Colocalizes with synaptonemal complex. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human CCNB1IP1 (cyclin B1 interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccnb1ip1 |
| Official Name | cyclin B1 interacting protein 1 [Source:MGI Symbol;Acc:MGI:2685134] |
| Ensembl ID | ENSMUSG00000071470 |
| Bio databases IDs | |
| Aliases | cyclin B1 interacting protein 1 |
| Synonyms | C14orf18, cyclin B1 interacting protein 1, Gm288, HEI10, mei4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccnb1ip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ubiquitin protein ligase activity
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- ubiquitin-protein transferase activity
- enzyme
- protein binding
- identical protein binding
- zinc-RING finger domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- non-insulin-dependent diabetes mellitus
- organismal death
role in cell
- growth
- expression in
- proliferation
- degradation in
- binding in
- ubiquitination in
- development
- colony formation
- invasiveness
- sphere formation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cell periphery
- chromosome
- synaptonemal complexes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccnb1ip1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chiasma assembly
- reciprocal meiotic recombination
- spermatid development
- blastocyst formation
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- synaptonemal complex
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- metal ion binding