Rbmxl2 Gene Summary [Mouse]

Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of mRNA splicing, via spliceosome. Predicted to be part of spliceosomal complex. Is expressed in central nervous system and sensory organ. Orthologous to human RBMXL2 (RBMX like 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rbmxl2
Official Name
RNA binding motif protein, X-linked-like 2 [Source:MGI Symbol;Acc:MGI:1923822]
Ensembl ID
ENSMUSG00000073894
Bio databases IDs NCBI: 76572 Ensembl: ENSMUSG00000073894
Aliases RNA binding motif protein, X-linked-like 2
Synonyms 1700012H05Rik, HNRNPG-T, HNRPGT, RBMX like 2, RNA binding motif protein, X-linked-like 2
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rbmxl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif
  • RBM1CTR (NUC064) family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
  • colorectal cancer
  • azoospermia
  • azoxymethane/dextran sodium sulfate induced colorectal cancer
regulates
role in cell
  • growth
  • apoptosis
  • expression in
  • function
  • stabilization in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rbmxl2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nuclear mRNA splicing, via spliceosome

Cellular Component

Where in the cell the gene product is active
  • U12-type spliceosomal complex

Molecular Function

What the gene product does at the molecular level
  • mRNA binding
  • snRNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.