Mex3a Gene Summary [Mouse]
Predicted to enable RNA binding activity. Predicted to be located in P-body and cytosol. Is expressed in central nervous system and sensory organ. Orthologous to human MEX3A (mex-3 RNA binding family member A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mex3a |
| Official Name | mex3 RNA binding family member A [Source:MGI Symbol;Acc:MGI:1919890] |
| Ensembl ID | ENSMUSG00000074480 |
| Bio databases IDs | |
| Aliases | mex3 RNA binding family member A |
| Synonyms | 2700083E18Rik, Gm411, mex-3 RNA binding family member A, RGD1564904, RKHD4, RNF162 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mex3a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- K homology (KH) RNA-binding domain, type I
- KH domain
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- K homology RNA-binding domain
- Zinc finger, C3HC4 type (RING finger)
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast cancer
- neoplasia
- epithelial cancer
- organismal death
- adenoid cystic carcinoma
- colorectal cancer
- lung adenocarcinoma
- lung adenocarcinoma formation
- ovarian cancer
- nasopharyngeal carcinoma
role in cell
- proliferation
- apoptosis
- expression in
- migration
- invasion by
- growth
- thenoyltrifluoroacetone sensitivity
- colony formation by
- suppression
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic mRNA processing body
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mex3a gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- cytoplasmic mRNA processing body
Molecular Function
What the gene product does at the molecular level
- RNA binding
- metal ion binding