Rab26 Gene Summary [Mouse]
Predicted to enable GMP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in several processes, including Golgi to plasma membrane protein transport; exocrine system development; and regulation protein catabolic process at presynapse. Located in secretory granule membrane. Orthologous to human RAB26 (RAB26, member RAS oncogene family). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rab26 |
| Official Name | RAB26, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:2443284] |
| Ensembl ID | ENSMUSG00000079657 |
| Bio databases IDs | |
| Aliases | RAB26, member RAS oncogene family |
| Synonyms | A830020M03RIK, RAB26, member RAS oncogene family, V46133 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rab26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Small GTPase of the Ras superfamily (ill-defined subfamily)
- Ras family
- GTPase
- enzyme
- protein binding
- Ras subfamily of RAS small GTPases
- GTP binding
- GMP binding
- small GTP-binding protein domain
- Rab subfamily of small GTPases
- Ras of Complex, Roc, domain of DAPkinase
- Rho (Ras homology) subfamily of Ras-like small GTPases
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- intracellular nanovesicle
- synaptic vesicle membrane
- secretory granule membrane
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rab26 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- exocrine system development
- regulated secretory pathway
- Golgi to plasma membrane protein transport
- regulation of exocytosis
Cellular Component
Where in the cell the gene product is active
- secretory granule membrane
- endosome
- Golgi membrane
- Golgi apparatus
- synaptic vesicle membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- GTPase activity
- GMP binding