Rmrp Gene Summary [Mouse]
Acts upstream of or within in utero embryonic development. Is expressed in early conceptus and secondary oocyte. Human ortholog(s) of this gene implicated in anauxetic dysplasia 1 and cartilage-hair hypoplasia. Orthologous to human RMRP (RNA component of mitochondrial RNA processing endoribonuclease). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Ribozyme |
| Official Symbol | Rmrp |
| Official Name | RNA component of mitochondrial RNAase P [Source:MGI Symbol;Acc:MGI:97937] |
| Ensembl ID | ENSMUSG00000088088 |
| Bio databases IDs | |
| Aliases | RNA component of mitochondrial RNAase P |
| Synonyms | 1110032O22Rik, AL732506.1, CHH, NME1, RMRPR, RNA component of mitochondrial RNAase P, RNA component of mitochondrial RNA processing endoribonuclease, RRP2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- colorectal cancer
- cartilage-hair hypoplasia
- anauxetic dysplasia
- anauxetic dysplasia type 1
- lung adenocarcinoma
- lung adenocarcinoma formation
- autosomal dominant polycystic kidney disease
- metaphyseal dysplasia without hypotrichosis
- multiple sclerosis
role in cell
- binding in
- expression in
- migration
- accumulation in
- phosphorylation in
- proliferation
- apoptosis
- growth
- colony formation
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm