Cxadr

Predicted to enable several functions, including PDZ domain binding activity; beta-catenin binding activity; and connexin binding activity. Predicted to be involved in several processes, including AV node cell-bundle of His cell adhesion involved in cell communication; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and neutrophil chemotaxis. Predicted to act upstream of or within negative regulation of cardiac muscle cell proliferation. Located in bicellular tight junction and neuron projection. Orthologous to human CXADR (CXADR Ig-like cell adhesion molecule). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cxadr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Cxadr gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Cxadr gene, providing context for its role in the cell.