Mr1

Predicted to enable T cell receptor binding activity and beta-2-microglobulin binding activity. Predicted to be involved in several processes, including T cell differentiation in thymus; defense response to Gram-positive bacterium; and positive regulation of T cell mediated cytotoxicity directed against tumor cell target. Predicted to act upstream of or within defense response to Gram-negative bacterium. Predicted to be located in endoplasmic reticulum membrane; endosome membrane; and plasma membrane. Predicted to be part of MHC class I protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human MR1 (major histocompatibility complex, class I-related). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Mr1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Mr1 gene, providing context for its role in the cell.